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Supplements for IBS-D

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Supplements for IBS-D Featured Image

Believe it or not, roughly 20% of the population have irritable bowel syndrome (IBS). Of this, our team of registered dietitians find that about half the IBS patients, at Ignite Nutrition, fall under the umbrella of diarrhea-predominant irritable bowel syndrome (IBS-D). Or, have IBS symptoms that alternate between diarrhea and constipation (IBS-M).

Diarrhea predominant IBS can be SO frustrating to manage with just nutrition basics. Loose stools cause urgency, which causes stress, which tends to make IBS symptoms worse!

Table of Contents

  1. Our approach to IBS-D management
  2. Dietary interventions
  3. Stress management strategies
  4. IBS-D medication
  5. IBS-D supplements
  6. The takeaway about IBS-D management

Our Approach to IBS-D Management

At Ignite, we first approach diarrhea management from 3 perspectives.

  • how quick the gut moves (motility)
  • stool consistency
  • working on abdominal pain and cramping that is so common when your bowels tend to empty quickly!

Today we are going to be discussing exactly how we manage IBS-D, as well as discussing some supplement options. At Ignite, we say ‘food first, medication second’. There are times when medication management is of course, necessary. But first, we try to get IBS symptoms under control with food, and IBS supplements options.

What we see as a result of this is a decrease in total doses of medicine required, and typically better quality of life for our patients!

Today, this post is sponsored by Fowler’s. They’re a company passionate about supporting patients with IBS and digestive disorders with supplement treatment options. We have partnered with them because we have seen that their products bring IBS symptom relief to patients when food isn’t quite enough!

First, let’s review common treatment options for IBS-D. They all fall into our four pillars of IBS management at Ignite, and may be addressed by your registered dietitian or gastroenterologist.

Dietary Interventions for IBS-D

  • Adequate dietary fibre (creates bulk in stool, absorbs excess water, and reduces sensation of urgency).
  • Elimination of FODMAP foods in the diet. (Reduces the amount of water moving into the bowels and reduces fermentation in the gut).
  • Limiting foods that increase motility such as fatty foods, spicy foods, and caffeine.

Stress Management Strategies for IBS-D

Stress management is key in IBS management. It is important because our brain is constantly communicating with the gut and sometimes stress can alter the message! In IBS, patients often experience anxiety around their food choices or have stressors in other areas of their lives. Stressors can lead to perceived pain in the gut, as well as altered gut motility. Some management strategies for stress include:

  • Cognitive Behavioural Therapy
  • Hypnotherapy
  • Meditation
  • Working on food & body trust

IBS-D Medication

Here are some examples of the most common medicines we see used to manage IBS-D.

  • Loperamide (slows bowels down)
  • Antispasmodics (reduces perception of pain and relaxes muscles in the gut)
  • Antidepressants (reduces perception of pain)
  • Rifaximin (reduces bacterial overgrowth in the bowel)
  • Eluxadoline (slows bowels down and reduce abdominal pain)

Many times, we see patients prescribed medication first. This may be appropriate depending on the severity of your IBS symptoms. But it is important to ask: how effective are these? What is the safety? And is there an alternative I should consider first?

At Ignite Nutrition, we aim to take a food-first approach to IBS management, meaning we prioritize dietary management strategies first. This does not mean medicine options are considered “bad” or unnecessary. But rather, that we explore them later in the management process, and occasionally, will suggest them earlier on if IBS symptoms are severe.

Challenges of Using Medicine for IBS-D

Although medication is often necessary for those with IBS-D symptoms, it does not come without challenges and potential risks. In fact, a recent review from Lacy et al. explored the risks and benefits of medication in IBS-D patients. One medicine that caught our attention, and is often used by our patients as it’s available as an over the counter IBS medicine, is loperamide.


This drug belongs to a category of drugs called opioid receptor agonists. It’s role is to slow contractions in the gut and alter the movement of water and electrolytes in the bowel. It is often used as an emergency therapy for acute diarrhea. But has become more routine in the symptom management of IBS-D. With many patients taking it daily, and understandably so. With urgency and a fear of incontinence, it’s no wonder patients rely on it to get them through flights, drives, meetings and more.

Although effective for many, it is important to understand the risks. Especially if you have cardiac issues or a history of pancreatitis. As side effects have been shown to exacerbate both conditions. Especially if used in larger doses or more frequently.

What we see as the more common issue with loperamide is that it causes constipation. Making it seem like your bowels are on a never ending rollercoaster.

This doesn’t mean that you shouldn’t take loperamide or that you need to panic. But what we think it brings to attention is a) can we reduce its use through proper management strategies and b) can we choose a more benign option, with less side effects and similar outcomes?

This is one out of many medications used in the management of IBS-D. The take-away from this example is that ALL medications should be re-evaluated regularly to determine safety and efficacy.

IBS-D Supplements

If dietary management strategies are inadequate for patients, we next consider supplement options. These are a great stepping stone between food and medications. Especially in patients that have mild IBS symptoms or situational flare-ups in diarrhea and other IBS symptoms.

One brand we’re proud to work with is Fowler’s digestive health. Fowler’s has been a long-standing name in the digestive healthcare industry. What sets them apart is that they strive to make safe products that don’t disrupt the body’s natural rhythms, like some medications do. In particular, Fowler’s offers two products for the management of IBS-D as supplement options:

Anti-diarrheal Oral Suspension for IBS-D

The Fowler’s anti-diarrheal oral suspension formula consists of attapulgite, a magnesium aluminum phyllosilicate. Attapulgite helps to bind water and bacteria in the digestive tract. Creating more solid stool in those with both acute or chronic diarrhea.

Attapulgite is non-systemic. Meaning it doesn’t get absorbed into the bloodstream. Keeping it isolated to the digestive tract until it is excreted.

In a comparison study between attapulgite and loperamide, attapulgite significantly improved stool consistency. Loperamide did act more quickly, however, at 48 hours, patients self-reported that the overall relief in IBS symptoms was equivalent – amazing! This shows us that there are safe and effective IBS supplement choices we can utilize prior to adding or increasing medications.

A green and yellow small rectangle shaped cardboard box with the words "Fowler's digestive health - fast relief from diarrhea and cramps" written on the front. It is laying on it's back on a marble surface and there is a picture of a spoon with pink coloured liquid in the spoon on the front of the box.

Anti-diarrheal Tablets for IBS-D

Looking for a travel-friendly option? Similar to the liquid formula, Fowler’s also offers attapulgite in tablet form. While both the liquid and tablets provide the same relief, the tablets are especially convenient for on-the-go. Each pack is lightweight and not too bulky, so can fit easily in a purse, carry-on or even fanny pack! Tablets are really great for airplane travel, as liquids can be tricky to put in a carry-on.

As mentioned above, diarrhea can come on quickly and urgently, especially when travelling. New cuisine, different time zones, the stress of flying or being in a car for 10 hours – it’s often a recipe for IBS symptoms! Try keeping these Fowler’s tablets on hand the next time you plan a trip. Or, throw them in your work bag to manage IBS symptoms at the office.

What we see in practice is patients often choose to use medications such as loperamide in anticipation of an episode of diarrhea, ie. for airplane flights or long drives, rather than traditionally for acute diarrhea – so in this case, using either the Fowler’s anti-diarrheal oral suspension or anti-diarrheal tablets slightly sooner could be used to prevent situational diarrhea.

on a wooden background there are various items laid out. These include an orange swim suit top with multicoloured swim bottoms. A memory box with the words "where to next" in-scripted on the front. A Canadian passport, a stripped green and white towel, some peppermint tea sachets, a phone and a green and yellow box with the words "Fowlers" written on the front. There is a package of unopened red pills next to the box.

Digestive Tonic for IBS-D

I don’t usually share too deeply into the day-to-day management of my own IBS symptoms, but it gives this story some important context. I think it provides valuable insight into how I can best help patients, living with the condition myself!

When I first decided to try Fowlers Digestive Tonic, I was skeptical. (As someone with not only IBS but issues with reflux – I expected liquid peppermint might not be the best for me). However, it quickly became my absolute favorite tool in my IBS management arsenal when I had IBS symptom flare ups from stress, or eating too many FODMAP’s. It’s because of my positive experience that I wanted to work with them!

Fowler’s digestive tonic includes a combination of peppermint oil and silicon. This natural remedy provides soothing relief from various symptoms of IBS including gas, bloating, and abdominal pain.

A green and yellow small rectangle shaped cardboard box with the words "Fowler's digestive health - aids in digestion, helps relieve gas, nausea and vomiting" written on the front. It is laying on it's back on a marble surface and there is a picture of a spoon with green coloured liquid in the spoon on the front of the box.

Peppermint acts as both an antispasmodic and an anti-inflammatory agent. Relaxing the smooth muscles of the gastrointestinal tract and creating an overall sense of ‘calm’ in our IBS’ers guts. It’s really no surprise this herb has become a leader in gut health, as it’s been used as a digestive aid for centuries!

The research on peppermint oil has yielded some promising results in IBS patients. A meta-analysis conducted in 2014 concluded that peppermint oil was two times more likely to improve overall IBS symptoms than a placebo.More specific to diarrhea, additional studies have also shown that peppermint oil has reduced stool frequency in IBS patients.6

How to Use Fowler’s Digestive Tonic:

  • Patients take it when they are noticing their digestive symptoms worsen
  • If they plan to consume something that might bother their stomach
  • If they’re having a flare up in IBS symptoms – for whatever reason! Changes in hormonal cycle, stress, sleep, and nutrition can cause fluctuations in IBS symptoms.

The Takeaway about IBS-D Management

  • Medication management is not benign. We, as health professionals, are responsible for keeping our patients safe. It is especially important to evaluate and re-evaluate medications prior to and during patient use. This applies not only to IBS-D management but other gastrointestinal diseases and beyond!
  • If food and lifestyle management is not providing ideal results, consider IBS supplement options. Natural digestive aids such as those from Fowler’s are a great ‘stepping stone’ between dietary management of IBS and medication strategies. They provide gentle relief in comparison to some other medications on the market today for IBS-D management.
  • Fowler’s anti-diarrheal oral suspension or the anti-diarrheal tablets and digestive tonic are both great options for everyday use. But also work great as a ‘rescue therapy’ during times when flare-ups are more likely. For example, when travelling, experiencing changes in diet, or after a period of antibiotic use.
2 green and yellow small rectangle shaped cardboard boxed with the words "Fowler's digestive health" written on the front. They are standing upright next to each other on a marble surface. On the front of one of them there is a picture of a spoon with green coloured liquid in the spoon on the front of the box.  On the other box there is a picture of a spoon with pink coloured liquid in the spoon on the front of the box.

Disclosure: This is a sponsored post. I was compensated for my time in writing this post. While the information conveyed may support clients’ objectives, the opinions expressed are my own and based on current scientific evidence. I do not engage in business with companies whose products or services do not match my personal and professional beliefs.

little tincture bottle, leaves, herbs and a mortar and pestle on a white background. There is a text box that reads "supplements for IBS-D"

FAQs about IBS-D supplements

What is the best thing to take for IBS-D?

This can depend on your exact symptoms and triggers, but one of my favourite IBS supplements to suggest for IBS-D is peppermint. Peppermint acts as both an antispasmodic and an anti-inflammatory agent. It helps to relax the smooth muscles of the GI tract and creating an overall sense of ‘calm’ in our IBS’ers guts. Learn more.

How do you treat IBS-D permanently?

Although there is no cure for IBS-D, there are some ways to help manage the IBS symptoms. At Ignite Nutrition, we say ‘food first, medication second’. We first try to get IBS symptoms under control with food, and IBS supplement options, and then look to medication if necessary. Learn more.

Categorized: Gut Health & IBS, Sponsored Post

2 responses to “Supplements for IBS-D”

  1. I can’t buy the Fowlers’ tablets in the US on Amazon. What’s a recommended US substitute?

    Also, I’ve tried peppermint pills before even ones that get great reviews for not causing reflux, but they still burn and I can’t tolerate them. Alternatives?

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  1. Drugbank.ca. (2018). Loperamide – DrugBank. [online] Available at: https://www.drugbank.ca/drugs/DB00836 [Accessed 16 Oct. 2018].

  2. Lacy BE. Review article: an analysis of safety profiles of the treatments for diarrhoea‐predominant irritable bowel syndrome. Aliment Pharmacol Ther. 2018;00:1–14. https://doi.org/10.1111/apt.14948

  3. Drugbank.ca. (2018). Attapulgite – DrugBank. [online] Available at: https://www.drugbank.ca/drugs/DB01574 [Accessed  16 Oct. 2018].

  4. DuPont HL, Ericsson CD, DuPont MW, Cruz LA, Mathewson JJ. A randomized, open-label comparison of non-prescription loperamide and attapulgite in the symptomatic treatment of acute diarrhea. Am J Med. 1990 Jun; 88(6A):20S-23S. https://pubmed.ncbi.nlm.nih.gov/2192554/#:~:text=Loperamide%20significantly%20reduced%20stool%20frequency,versus%20attapulgite%2C%2019.5%20hours).

  5. Khanna R, MacDonald JK, Levesque BG. Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis. J Clin Gastroenterol. 2014 Jul;48(6):505-12. https://pubmed.ncbi.nlm.nih.gov/24100754/

  6. Shams R, Oldfield EC, Copare J, Johnson DA. Peppermint Oil: Clinical Uses in the Treatment of Gastrointestinal Diseases. JSM Gas-troenterol Hepatol 2015 Jan;3(1): 1036.2. https://www.semanticscholar.org/paper/Peppermint-Oil-%3A-Clinical-Uses-in-the-Treatment-of-Shams-Copare/693116e195a255da7171d6c869698b2ea458704a